國立臺灣海洋大學水產養殖系張清風老師研究室

海洋生物與生殖內分泌研究室 (Molecular Biology & Endocrinology Laboratory)

 

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張清風  終身特聘教授

   

 

 

      歷:

美國華盛頓州立大學 動物科學系(博士,1986)

 

美國華盛頓州立大學 動物科學系(碩士,1982)

 

臺灣省立海洋學院 水產製造學系(學士,1975)

   

    職:

國立臺灣海洋大學終身 特聘教授(2004~)

國立臺灣海洋大學 校長(2012~)

 

學術專長:

水生動物生理,海洋生物,生殖生理與內分泌

 

 

獲得獎項:

國科會優等研究獎 (1990)

 

國科會傑出研究獎三次(1991-19921994-19961996-1998)

 

中華民國第三十一屆「十大傑出青年」(1993)

 

國科會第一次特約研究員獎(1998~2001)

 

國科會第二次特約研究員獎(2001~2004)

 

國立臺灣海洋大學「終身特聘教授」(2004/08~)

 

教育部第四十八屆學術獎(2004)  

 

國科會傑出特約研究員獎(2004)

 

教育部第10屆國家講座(2006)

 

國立臺灣海洋大學(校級)傑出校友(學術類)(2007)

 

國立臺灣海洋大學98學年度「校級教學優良教師獎」(2010)

 

國科會2012年度「臺法科技獎」(2012)

 

美東華人學術聯誼會「傑出專業成就獎」(2013)

 

中華實驗動物學會「2013年傑出貢獻獎」(2013)

 

中國生物學會「生物科學研究傑出獎」(2013)

 

美國華盛頓州立大學動物科學傑出校友(2014)

 

中華民國105年海運有功人員獎(2016)

 

日本太平洋科學學會「Shinkishi Hatai Medal Award(2016)

 

 

電子信箱:

B0044@email.ntou.edu.tw

     話:

02-24622192  分機 1000~1004(O)5209(L)

     真:

02-24623563(O)02-24621579(L)

   

 


 

 

重要經歷:

國立臺灣海洋大學副教授(1986/2~1990),教授(1990~)
            終身特聘教授(2004~)

 

國立臺灣海洋大學水產養殖系系主任(1986/08~1992/07)

 

國立臺灣海洋大學教務長(2003/03~2006/03)

 

國立臺灣海洋大學水產生物科技頂尖研究中心主任(2006/04~2007/08,
 2009/08~2011/04)

 

國立臺灣海洋大學校長(2012/08~)

 

行政院國家科學委員會 生物科學發展處處長(2007/08~2009/07)

 

國立臺灣海洋大學  副校長(2009/08~2011/04)

 

行政院國家科學委員會 副主任委員(2011/5/1~2012/5/19)

 

法國國家科學研究中心(CNRS)訪問研究員(8個月)

 

日本北里大學分子內分泌研究室訪問研究員(2個月)

 

日本國立養殖研究所訪問研究員(2個月)

 

日本國立基礎生物研究所訪問研究員(4個月)

 

日本國立琉球大學海洋生物研究所客座教授(4個月)

 

臺灣水產學會 理事、常務理事(2011/1/17~2013/1/16)

理事長 (2012~2016)、榮譽理事長(2017~)

 

中華海洋事業協會理事長(2016~)

 

亞太比較內分泌學會理事長(2017~2020)

亞太比較內分泌國際委員(2008~2016)

 

臺灣海洋生物技術學會理事長(2016/12/26~2018/12/25)

教育部學術審議委員會 委員、常務委員

 

國家實驗研究院臺灣海洋科技研究中心 諮詢委員

 

中央研究院細胞與個體生物學研究所 諮議委員(2010/9/1~2013/8/31)

 

農委會特有生物研究中心 研究諮詢委員(2008/3/31~)

 

國際生物學聯合會中華民國委員會(IUBS) 委員(2010/1/1~2012/12/31)

 

魚類內分泌國際委員(2008)

 

考試院高等考試及格

 

考試院「水產技師」

 

考選部典試委員、命題委員、閱卷委員

 

國際學術期刊編輯委員

 

 

 

研究方向:  

本研究室主要以分子遺傳基因、細胞生物、細胞培養、生化、免疫與生理等方向探討水產動物 (魚類、蝦類與珊瑚等) 之生理、內分泌生殖與環境適應等重要生命科學之問題,著重在基礎及應用研究。主要研究方向為 (1) 激素基因及激素受體基因表現及調控,(2)內分泌生理,(3)生殖生理,(4) 環境適應生理,(5) 性別分化與性轉變

 

研究之策略與擬解決問題:

探討海洋生物及養殖生物重要生命科學問題及環境生理調適等問題。利用個體、器官、組織、細胞、分子、遺傳及細胞培養等策略,進行整合性的研究。

 

最近進行之研究課題: 

1.          黑鯛性別分化與性轉變機制及其內分泌作用之研究

2.          石斑魚 性別分化與青春期啓動之研究

3.          珊瑚內分泌與生殖之研究

4.          鰻魚的生殖生理之基礎與應用研究

5.          環境對於類生理的影響

 

教學課程:

研究所:內分泌學,魚類生殖生理學 。

大學部:生物學,魚類生理學,魚類生理學實驗。

 

著作目錄:

1.

Jeng, S. S., Wang, C. M., and Chang, C. F. 1978.  Existence of an estrogen-like compound in the ovary of the shrimp Parapenaeus fissurus.  Gen. Comp. Endocrinol. 36, 211-214.  (SCI)

2.

Chang, C. F., and Estergreen, V. L.1983. Development of a direct enzyme immunoassay of milk progesterone and its application to pregnancy diagnosis in cows. Steroids. 41, 173-195.  (SCI)

3.

Wimpy, T. H., Chang, C. F., Estergreen, V. L., and Hillers, T. K. 1986. Milk progesterone enzyme immunoassay: modifications and a field trial for pregnancy detection in dairy cows. J. Dairy Sci. 69, 1115-1121.  (SCI)

4.

De Silva, M., Tjoelker, L., Chang, C. F., and Reeves, J. J. 1986.  Ovarian response to active immunization against luteinizing hormone in the cow. Theriogenology. 26, 89-100.  (SCI)

5.

Chang, C. F., McFarland, S. Y., and Reeves, J. J. 1987.  Active immunization of heifers against prostaglandin F2αPotential as a sterilization vaccine. J. Anim. Sci. 64, 1090-1098.  (SCI)

6.

Chang, C. F. and Reeves, J. J. 1987.  Postpartum interval in beef cows shortened by enclomiphene. J. Anim. Sci. 65, 217-223.  (SCI)

7.

Chang, C. F., Robert, A. J., and Reeves, J. J. 1987.  Increased luteinizing  hormone secretion and ovarian function in heifers actively immunized against estrogen and progesterone. J. Anim. Sci. 65, 771-776.  (SCI)

8.

Johnson, H. E., DeAvila, D. M., Chang, C. F., and Reeves, J. J. 1988. Active immunization of heifers against Luteinizing Hormone-releasing hormone, human chorionic gonadotropin and bovine luteinizing hormone. J. Anim. Sci. 66, 719-726.  (SCI)

9.

Robert, A. J., Chang, C. F., Schally, A. V., and Reeves, J. J. 1989. Luteinizing hormone concentrations in serum of postpartum beef cows injected with microencapsulated luteinizing hormone releasing hormone analog. J. Anim. Sci. 67, 2730-2734.  (SCI)

10.

Reeves, J. J., Chang, C. F., deAvila, D. M., Grieger, D. M., Johnson, H. E., and Roberts, A. J. 1989.  Vaccine against endogenous hormones: a possible future tool in animal production. J. Dairy Sci. 72, 3363-3371.  (SCI)

11.

Chang, C. F., and Yueh W. S. 1989. Gonadal histology and steroidal levels in the male protandrous black porgy.  In "Current Topics in Marine Biotechnology". Edited by S. Miyachi, I. Karube and Y. Ishida. pp. 327-332. Fuji Technology Press Ltd. Tokyo. Japan.

12.

Chang, C. F., and Chen, M. R. 1989. The distribution and characteristic of steroid-binding protein in fish and shrimp. In "Current Topics in Marine Biotechnology". Edited by S. Miyachi, I. Karube and Y. Ishida. pp. 333-336. Fuji Technology Press Ltd. Tokyo. Japan.

13.

Yueh, W. S., Lin, S. F., and Chang, C. F. 1990. Effects of LHRH-A and HCG on spermiation volume, concentration of milt and sex steroids in black porgy, Acanthopagrus schlegeli. J. Fish Soc. Taiwan. 17, 65-72.

14.

Chang, C. F., and Chen, M. R. 1990. The difference in the degree of steroid-binding activity in fishes. Bull. Inst. Zool., Academia Sinica. 29, 41-47.  (SCI)

15.

Chang, C. F., and Yueh, W. S. 1990. Oocyte maturation in protandrous black porgy, Acanthopagrus  schlegeli, stimulated by enclomiphene and luteinizing hormone releasing hormone analogue. Bull. Inst. Zool., Academia Sinica. 29, 173-179.  (SCI)

16.

Chang, C. F., and Chen, M. R.  1990. Fluctuation in sex steroids and sex steroid-binding protein during the development and annual cycle of the male common carp, Cyprinus  carpio. Comp. Biochem. Physiol. 97A, 565-568.  (SCI)

17.

Chang, C. F., and Yueh, W. S. 1990. Annual cycle of gonad histology and steroid profiles in the juvenile males and adult females of the protandrous black porgy, Acanthopagrus schlegeli. Aquaculture. 91, 179-196.  (SCI)

18.

Chang, C. F., Yueh, W. S., and Lee, M. F. 1991. Effects of LHRH-A and HCG on the steroid profiles of bisexual and mature male and female protandrous black porgy, Acanthopagrus schlegeli. Aquaculture. 92, 83-92.  (SCI)

19.

Chang, C. F. and Chen, M. R. 1991. Lack of correlation found between plasma sex steroids and sex steroid-binding capacity during the annual cycle of the female common carp. Bull. Inst. Zool., Academia Sinica. 30, 81-86.  (SCI)

20.

Chang, C. F. and Lin, S. J. 1991. An enkephalin analog stimulates growth of tilapia. Fish Physiol. Biochem. 9, 101-106.  (SCI)

21.

Chang, C. F., Hu, H. J., Tang, H. C., and Sun, L. T.1992. Stimulation of ovulation in ayu, Plecoglossus  altivelis, by treatment with antiestrogens and luteinizing hormone releasing hormone analog. Aquaculture. 101, 329-336.  (SCI)

22.

Chang, C. F., Hu, H. J., and Tang, H. C. 1992. Effects of photoperiod and temperature on testicular development in male ayu, Plecoglossus altivelis. Environ. Biol. Fishes. 34, 309-314.  (SCI)

23.

Sun, L. T., Hu, H. J., Tang, H. C., Huang, C. F., and Chang, C. F. 1992. Changes of sex steroid concentrations in female and male ayu  (Plecoglossus altivelis)  stimulated by  luteinizing hormone releasing hormone analog. Bull. Inst. Zool., Academia Sinica 31, 57-64.  (SCI)

24.

Chang, C. F. and Lee, Y. H. 1992. Purification of the sex steroid- binding protein from common carp plasma. Comp. Biochem. Physiol. 101B, 587-590.  (SCI)

25.

Sun, L. T., Chen, G. R., and Chang, C. F. 1992. The Physiological responses of tilapia exposed to low temperatures. J. Therm. Biol. 17, 149-153.  (SCI)

26.

Lee, M. F., Chang, C. F., Huang, J. D., and Schally, A. V. 1993. Microencapsulated LHRH analog accelerates spermiation in protandrousblack porgy, Acanthopagrus  schlegeli. Bull. Inst. Zool., Academia Sinica. 32, 32-38.  (SCI)

27.

Chang, C. F., Lee, F. Y., and Huang, Y. S. 1993. Purification and characterization of vitellin from the mature ovaries of prawn, Penaeus monodon. Comp. Biochem. Physiol. 105B, 409-414.  (SCI)

28.

Chang, C. F., Shih, T. W., and Hong, H. H. 1993. Purification and characterization of vitellin from the mature ovaries of prawn, Macrobrachium rosenbergii. Comp. Biochem. Physiol. 105B, 609-615.  (SCI)

29.

Chang, C. F., Hu, H. J., and Sun, L. T.  1993. Effects of temperature and photoperiod on ovarian development in female ayu, Plecoglossus altivelis. J. Therm. Biol. 18, 197-201.  (SCI)

30.

Tsai H. J., Chi, W. K., Chang, C. C., Kao, T. T., and Chang, C. F. 1993. Enhacement of tilapia growth by dietary administration of recombinant yeast lysates as a supplement. J. Fish Soc. Taiwan 20, 339-345.

31.

Sun L. T., Chen, G. R., and Chang, C. F. 1994. Characteristics of blood parameters and gill Na+-K+-ATPase in chilled comatose tilapia cultured in various salinities. Comp. Biochem. Physiol. 107A, 641-646.  (SCI)

32.

Chang, C. F., Lee, M. F., and Chen, G. R. 1994. Estradiol-17Β associated with the sex reversal in protandrous black porgy, Acanthopagrus schlegeli. J. Exp. Zool. 268, 53-58.  (SCI)

33.

Chang, C. F., Lee, Y. H., Yoshida, T., and Sun, L. T. 1994. Characterization of the plasma sex steroid-binding protein in eel  (Anguilla japonica) . Comp. Biochem. Physiol. 108B189-197.  (SCI) .

34.

Chang, C. F., Lee, F. Y., Huang, Y. S., and Hong, T. H. 1994. Purification and characterization of the female-specific protein  (vitellogenin)  in mature female hemolymph of prawn, Penaeus monodon. Invert. Reprod. Dev. 25, 185-192.  (SCI)

35.

Lin, S. J., Tin, Y. Y. and Chang, C. F. 1994. The stimulatory effects of 3,5,3'-triiodo- L-thyronine on the content of liver soluble protein in tilapia. J. Fish Soc. Taiwan. 21, 361-368.

36.

Chang, C. F. and Shih, T. W. 1995. Reproductive cycle of ovarian development and vitellogenin profiles in the freshwater prawns, Macrobrachium rosenbergii. Invert. Reprod. Dev. 27, 11-20.  (SCI)

37.

Chang, C. F. and Lin, S. J. 1995. Immersion in bovine insulin stimulates growth of tilapia. Reprod. Nutr. Dev. 35, 95-103.  (SCI)

38.

Chang, C. F., Sun, L. T. and Chen, G. R. 1995 Acute responses of blood parameters and comatose effects in salt-acclimated tilapia exposed to low temperatures. J. Therm. Biol. 20, 299-306.  (SCI) .

39.

Chang, C. F., Yueh, W. S., Lee, M. F. and Schally A. V. 1995. A microencapsulated analog of LHRH accelerates maturation but without stimulating sex reversal in the protandrous black porgy, Acanthopagrus schlegeli. Reprod. Nutr. Dev. 35, 339-349.  (SCI)

40.

Chen, G. R., Sun, L. T., Lee, Y. H. and Chang, C. F.1995. Characteristics of blood in common carp  (Cyprinus carpio)  exposed to low temperatures. J. Applied Aquaculture 5, 21-31.

41.

Chang, C. F., Lan, S. C., and Chou, H. Y. 1995. Gonadal histology and plasma sex steroids during sex differentiation in grey mullet, Mugil cephalus. J. Exp. Zool. 272, 395-406.  (SCI)

42.

Chang, C. F., and Jeng S. R. 1995.  Isolation and Characterization of the female-specific protein  (vitellogenin)  in mature female hemolymph of the prawn, Penaeus chinensis. Comp. Biochem. Physiol. 112B, 257-263.  (SCI)

43.

Chang, C. F., Lau, E. L., and Lin B. Y. 1995. Estradiol-17β suppresses testicular development and stimulates sex reversal in protandrons black porgy, Acanthopagrus schlegeli. Fish Physiol. Biochem. 14, 481-488.  (SCI)

44.

Chang, C. F., Lan, S. C., and Pan, P. S. 1995. Feed administration of estradiol-17β stimulates female differentiation in juvenile grey mullet, Mugil cephalus. Zool. Stud. 34, 257-264.  (SCI)

45.

Chang, C. F., Lau, E. L., and Lin, B. Y.  1995. Stimulation of spermatogenesis or of sex reversal according to the dose of exogenous estradiol-17β in juvenile males of protandrous black porgy, Acanthopagrus schlegeli. Gen. Comp. Endocrinol. 100, 355-367.  (SCI)

46.

Chang, C. F., Lau, E. L., Lin, B. Y., and Jeng, S. R. 1996. Characterization of vitellogenin induced by estradiol-17β in protandrons black porgy, Acanthopagrus schlegeli. Fish Physiol. Biochem. 15, 11-19.  (SCI)

47.

Chang, C. F., Jeng, S. R., Lin, M. N., and Tin, Y. Y. 1996. Purification and characterization of vitellin from the mature ovaries of prawn, Penaeuschinensis. Invert. Reprod. Dev. 29, 87-93.  (SCI)

48.

Lee F. Y., and Chang, C. F. 1997. The concentrations of vitellogenin  (vitellin)  and protein in hemolymph, ovary and hepatopancreas in different ovarian stages of the freshwater prawns, Macrobrachium rosenbergii. Comp. Biochem. Physiol.117A, 433-439.  (SCI)

49.

Yueh, W. S., and Chang, C. F. 1997. 17a, 20β, 21- Trihydroxy-4- pregnen-3-one and 17a, 20β-dihydroxy-4-pregnen-3-one stimulate spermiation in protandrous black porgy, Acanthopagrus schlegeli.  Fish Physiol. Biochem. 17, 187-193.  (SCI)

50.

Lau, E. L., Lin, B. Y., Lee, F. Y., Sun, L. T., Dufour, S., and Chang, C. F. 1997.  Stimulation of testicular function by exogenous testosterone in male protandrous black porgy, Acanthopagrus schlegeli. J. Fish Biol. 51, 327-333.  (SCI)

51.

Huang, Y. S., Schmitz, M., Le Belle, N., Chang, C. F., Querat, B., and Dufour, S. 1997. Androgens stimulate gonadotropin-II b subunit in the eel pituitary cells in vitro. Mol. Cell Endocrinol.131, 157-166.  (SCI)

52.

Chang, C. F., Lin, B. Y., Lau, E. L., Lee, M. F., Yueh, W. S., Chang, C. N., Lee, Y. H., Tacon, P., Lee, F. Y., Du, J. L., and Sun, L. T. 1997. The endocrine mechanism of sex reversal in the protandrous black porgy, Acanthopagrus schlegeli: a review. Chin. J. Physiol. 40, 197-205.  (SCI)

53.

Lee, F. Y, Shih, T. W., and Chang, C. F. 1997. Isolation and characterization of the female specific protein  (vitellogenin)  in mature female hemolymph of the freshwater prawn, Macrobrachium rosenbergii: comparison with ovarian vitellin. Gen. Comp. Endocrinol. 108, 406-415.  (SCI)

54.

Chang, C. F. and Lin, B. Y. 1998. Estradiol-17β stimulates aromatase activity and reversible sex change in protandrous black porgy, Acanthopagrus schlegeli. J. Exp. Zool. 280, 165-173.  (SCI)

55.

Huang, Y. S., Le Belle, N., Schmitz, M., Chang, C. F., Vernier, P., Querat, B., and Dufour, S. 1998. In vivo and in vitro effects of sex steroids on gonadotropin  (GtH-II)  synthesis in the female European eel. Ann. New York Academy Sci. 839, 348-350.  (SCI)

56.

Chang, C. F., Hung, C. Y., Chiang, M. C., and Lan, S, C. 1999. The concentrations of plasma sex steroids and gonadal aromatase during controlled sex differentiation in grey mullet, Mugil cephalus. Aquaculture 177, 37-45.  (SCI)

57.

Lee, F. Y., and Chang, C. F. 1999. Hepatopancreas is the likely organ of vitellogenin synthesis in the freshwater prawn, Macrobrachium rosenbergii. J. Exp. Zool. 284, 798-806.  (SCI)

58.

Lee, Y. H., Du, J. L., Yueh, W. S., Lee, F. Y., Tanaka, H., and Chang, C.F. 1999. 17b–Estradiol, but not testosterone stimulates gonadotropin II concentrations in the protandrous black porgy, Acanthopagrus schlegeli Bleeker. Fish Physiol. Biochem. 21, 345-351.  (SCI)

59.

Yueh W. S., and Chang, C. F. 2000. Morphological changes and competence of the maturing oocytes in the protandrous black porgy, Acanthopagrus schlegeli. Zool. Stud. 39, 114-122.  (SCI)

60.

Lee, Y. H., Lee, F. Y., Yueh, W. S., Tacon, P., Du, J. L., Chang, C. N., Jeng, S. R. , Tanaka, H., and Chang, C. F. 2000. Profiles of gonadal development, sex steroids, aromatase activity and gonadotropin II in the controlled sex changes of protandrous black porgy, Acanthopagrus schlegeli. Gen. Comp. Endocrinol. 119, 111-120.  (SCI)

61.

Tsai, C. L., Wang, L. H., Chang, C. F., and Kao, C. C. 2000. Effects of gonadal steroids on brain serotonergic and aromatase activity during the critical period of sexual differentiation in tilapia, Oreochromis mossambicus. J. Neuroendocrinol. 12, 894-898.  (SCI)

62.

Jeng, S. R., Chen, G. R., Lai, J. Y., Huang, Y. S., Dufour, S., and Chang, C. F. 2000. Sex steroids and pituitary extract increase gonadotropin II content in the pituitary of aquacultured Japanese eel Anguilla japonica. J. Fish. Res. 9: 97-108.

63.

Du. J. L., Lee, C. Y., Tacon, P., Lee, Y. H., Yen, F. P., Tanaka, H., Dufour, S. and Chang, C. F. 2001. Estradiol-17b stimulates gonadotropin II expression and release in the protandrous male black porgy, Acanthopagrus schlegeli Bleeker: A possible role in sex change. Gen. Comp. Endocrinol. 121, 135-145.  (SCI)

64.

Law, W. Y., Chen, W. H, Song, Y. L., Dufour, S., and Chang, C. F. 2001. Differential in vitro suppressive effects of steroids on the leukocyte phagocytosis in tilapia and common carp. Gen. Comp. Endocrinol. 121, 163-172.  (SCI)

65.

Lee, Y. H., Du, J. L., Yen, F. P., Lee, C. Y., Dufour, S., Sun, L. T. and Chang, C. F. 2001. Regulation of plasma gonadotropin II secretion by sex steroids, aromatase inhibitors and antiestrogens in the protandrous black porgy, Acanthopagrus schlegeli Bleeker. Comp. Biochem Physiol. 129B, 399-406.  (SCI)

66.

Lee, Y. H., Du, J. L., Yueh, W. S., Lin, B. Y., Huang, J. D., Lee, C. Y., Lee, M. F., Lau, E. L., Lee, F. Y., Morrey, C., Nagahama, Y., and Chang, C. F. 2001. Sex change in the protandrous black porgy, Acanthopagrus schelgeli: a review in gonadal development, estradiol, estrogen receptor, aromatase activity and gonadotropin. J. Exp. Zool. 290, 715-726.  (SCI)

67.

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      更新日期2017年10月31日